John M. Wetzel, Ph.D. has served full time as Principal of Wetzel Chemistry Consulting, LLC since 2006. For clients engaged in drug development, he has managed synthetic route scouting, process optimization, analytical method development/qualification, structure elucidation, impurity qualification, salt screening, …
Background: Dr. Wetzel’s consulting services are provided under confidentiality. His contributions to some representative projects are described below in general terms. Central Findings: Project 1: The original, laboratory-scale synthetic process for a drug candidate was modified to improve safety and …
Wetzel Chemistry Consulting, LLC Albany, OH, 2005-present, Principal How Clients Benefited in Drug Development: Novel active pharmaceutical ingredient (API) manufacturing processes were developed API and impurity structures were elucidated and impurities qualified API polymorphs were characterized Analytical and bioanalytical methods …
The Johns Hopkins University, Ph.D., Chemistry, 1988 Dissertation: Part I: Silicon-promoted ring contractions in the synthesis of carbocyclic spiro compounds. Total synthesis of (-)-solavetivone. Part II: The trimethylsilyl cationic species as a bulky proton. Application to chemoselective dioxolanation. Advisor: Prof. …
University at Buffalo, Amherst, NY, Feb 2009, Masters in Chemical and Biological Engineering University at Buffalo, Amherst, NY, May 2006, Bachelors in Chemical and Biological Engineering SBM Polytechnic, Mumbai, India, June 2004, Diploma in Chemical Engineering
PrismEdge Chemical Consulting, Sugar Land, TX, April 2024 – Present, Founder and CEO AlixPartners LLP, Houston, TX, Jan 2023 – Feb 2024, Director and Chemicals Subject Matter Expert Wood Mackenzie, Houston, TX, Feb 2013-Jan 2023, Head of Chemicals and Monomer …
AiCHE Tau Beta Phi , Engineering Honor society
BS Che Penn State University 1972 MS ChE Stanford University 1975 PhD ChE Stanford University 1980 Advisor: Michel Boudart. Thesis title “The Preparation and Use of Platinum Powders in Adsorption and Catalysis.”
40 years in petroleum industry. Two with Mobil Research and Development 1972-1974. 38 years with Chevron Technology Company (and similar names) 1977-2015. Various positions from Research Engineer to Senior Consultant. Focus was on heterogenous catalysis and in managing mercury throughout …
ACS American Chemical Society (retired) ACC&CE Association of Consulting Chemists and Chemical Engineers
